But what has happened out of sight, within the body of the machine, has been completely enhanced though. It doesn’t have a flashy new design, or a vastly upgraded screen. So to look at the 2022 Apple MacBook Pro 14”, you might feel a little underwhelmed - we certainly were. ![]() If you’ve used Apple MacBook Pro models in the past, you’ll be well aware of the striking industrial design, Retina screens and the optimised marriage of in-house hardware and software combining to make a highly desirable, hugely capable laptop for music production. if you want more guidance, head to our buying advice section. So, the best laptop for music production should be powerful and lightweight, while also rocking a good battery capacity, for those situations where you’re away from mains power. Some of the highest spec, beefiest laptops also weigh a fair amount, and your shoulders will quickly tire of lugging those behemoths around. Instead, you need a laptop with enough power to handle the latest software and expanding file sizes, with enough juice in the tank to cope with whatever you may need down the line.įor any DJs or traveling musicians reading this guide, weight - and portability - is likely to be another major factor. While the basic requirement for most DAWs is a multi-core processor, around 4GB of RAM, and a few gigabytes of storage, this won't be enough for real-world applications.īuying a music laptop based on the ‘minimum recommended’ specs is a recipe for future angst and a need for an early upgrade. When it comes to choosing the best music production laptop for your home studio, you'll want to pay close attention to the power and memory specs of the machine you're eyeing. Regardless of which platform you opt for - Apple or Windows - there are some considerations that remain consistent. How we test laptops for music productionĪll of this is great for the consumer, as it gives us genuine choices when it comes to music production.
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![]() It's about having fun, making memories, and sharing long-overdue conversations while answering one of life's more important questions, "Red or white?" Give it a try. Being a Twister isn't about making a museum-worthy work of art and outdoing your girlfriends. So, you like having a good time, hanging out with your friends, and skipping the pricey bar tab-but what if you're not a trained artist? Luckily, that doesn't matter! Most of our guests have little to no painting experience. Wine, fun, and friends are the only things you need for a ladies' night to remember. Our paint and sip parties are your squad's perfect destination. What better way to treat yourself than to gather your friends for a girls' night out? When looking for things to do for girls' night, you don't have to settle for ridesharing to the local bar (again) or re-watching that '90s chick flick for the 100th time! You can spend quality time with friends without repeating the same old girls' night out ideas. It's no wonder giving yourself some time for self-care is so important. Between errands, family, and just being an adult, you've got a lot going on. ![]() What better way to crack a smile than with a glass of your favorite beverage in one hand and a paintbrush in the other!? Why Come to Painting with a Twist for a Girls' Night Out? And when you book a private event, you get to choose what you want to paint from our library of more than 15,000 pieces of art! After all, on ladies' night, laughing is your one-step skincare routine. Then, grab your favorite beverage and paint the town red, white, or rosé! What Will You Paint at a Girls' Night Out?Įach Painting with a Twist studio has an assortment of unique painting events to choose from! Whether the art is seasonal, still life, an animal, or one of our many Disney-themed paintings, you can be sure you'll live, laugh, and love every stroke. Want the studio all to yourselves?įill out the form below to book your private paint party with all your girlfriends. You just bring your besties, favorite beverages, and must-have snacks! Just find your location and select an event from the calendar to start planning your girls' night out. We'll provide the laid-back ambiance, painting supplies, and step-by-step instructions. At Painting with a Twist, your next girls' night out can be an intimate paint and sip party where you and your friends let your best selves shine. What Are Girls' Night Out Paint and Sip Events Like?Ī blank canvas, a casual atmosphere, and a glass half-full. Just sit back, "wine" down, and enjoy one of the most fun things to do for girls’ night! Would you rather join an event already on our calendar? No problem! Find a location near you and choose from the upcoming calendar events to get started. Book a private paint party using the form below and choose what to paint from our library of fun artwork - no need to worry about who's going to clean up or what you're going to wear. At your local Twist, you can sip, snack and connect with your friends as you paint with the friendly help of one of our energetic artists. ![]() "As Project Manager, Kenneth will be able to help organize and leverage the tremendous amount of energy and expertise at the table." "Blockland is an exciting initiative for Northeast Ohio because it is a true grassroots community effort," added JumpStart CEO Ray Leach, who also co-chairs one of Blockland's eleven governing nodes. Prior to joining Blockland Cleveland, Clarke spent more than two decades in executive leadership positions at some of the Midwest's leading nonprofit, educational and cultural organizations. He is the immediate-past President & CEO of the Pritzker Military Museum & Library in Chicago and served as Associate Vice President for Development and Marketing at Safer Foundation, Executive Director of The Poetry Center at the School of the Art Institute, Director of Development (Midwest Region) for The Ohio State University and Development Officer at the Ohio Historical Society.Ĭlarke's hiring comes on the heels of a first-of-its-kind partnership with Toronto-based Blockchain Research Institute (BRI), which saw JumpStart join BRI on behalf of Northeast Ohio. This agreement allows Blockland to provide Greater Cleveland entrepreneurs and existing businesses valued under $1 billion with free access to the institute's significant library of blockchain research. Meanwhile, the first Blockland Solutions Conference will take place at the Huntington Convention Center of Cleveland from Dec. Destination Cleveland will serve as the primary manager of the Solutions Conference given its team's expertise in the meeting and conventions industry and its role as the region's destination marketing and management organization. The convention and visitors bureau staff will provide in-kind support including conference management, marketing and communications, and operations and administration. "Destination Cleveland is honored to be an integral contributor to the Blockland initiative and Solutions Conference," said David Gilbert, President and CEO of Destination Cleveland. "Both the Blockland effort and the conference are unprecedented for Cleveland, and there is risk associated with trying something different. We will apply our expertise to making the event the best it can be and learn from the experience so that future endeavors can be even better."Ĭleveland is building a blockchain technology ecosystem called Blockland. This unprecedented, community-wide movement puts Cleveland at the forefront of blockchain thought leadership as developers, business leaders, government representatives, entrepreneurs, philanthropic organizations and universities collaborate to explore and accelerate the adoption and growth of this disruptive technology. JumpStart unlocks the full potential of diverse and ambitious entrepreneurs to economically transform entire communities. For more information, visit follow on Twitter.ĭestination Cleveland is Cleveland's destination marketing and management organization. This private, non-profit organization's mission is to drive economic impact and stimulate community vitality for Greater Cleveland through leisure and business travel. ![]() ![]() 10 and love the game more and more as the years go by. Newest versions are incredible, and I can always be ready for another run at a moments notice. The streamlining of this game has breathed new life into it, and it's no Lite game. Plenty of crunch and complexity to play around in. This one feels like home, a classic that has so many QOL features (with more added pretty regularly!) and interesting things to do. Rift Wizard - blow up shit, make crazy spell combos, use your brain because every move, spell, and item counts. Roguelike distilled in some ways to it's purest form, and in the spell systems case, blown out in fabulous fashion. Rift Wizard has become one of my most played in recent years.Ĭogmind - I'm bad at this game, hoping to play more this year and change that! There's a ton of really cool systems at work here, and the ASCII/Tile art is all gorgeous. I've only won once, and it was by the seat of my pants. Need to play it more to get better and understand the systems fully. I could go on and on about the work put into this, and I've barely scratched the surface apparently. Golden Krone Hotel - This one is a bit lighter in some ways to the others preceding it on the list, but still a very fun game I really enjoyed, and still enjoy coming back to for a run or two once a month-ish. Honestly should be recommended more as an on-ramp for people new to the roguelike genre. Has its own quirks and ideas but really gets you into the system and feel of the game. The Ground Gives Way (TGGW) - this game has such a great feeling, very streamlined design but with a million things to find and make work. ![]() However, the single or double inoculation did not modify the nutrient content in papaya seedlings.īiofertilizer rhizobacteria seed inoculation organic matter. intraradices was applied as a single inoculant. We conducted four studies with Known You 1 and Sunrise papaya seedlings to determine the combined influence of wind and water deficit on. The double inoculation (seed and seedling) promoted higher growth and biomass of the crop than single inoculation (only seedlings), when organic matter was added at an intermediate dose (25 or 35%) and G. intraradices) for a total of 20 treatments, in a completely randomized design. This means that if plants aged 0-4 months do not receive proper fertilizing care, then further growth is difficult to improve, even if the plants are. Even when the plant is 0-4 months old, it is a critical period for the plant. To grow papaya from seeds, start by selecting ripe and fresh seeds from the papaya fruit. All treatments were applied as single or combined inoculants ( A. Papaya plants absolutely need to be fertilized fertilization is very helpful for growth and good fruit production. Third image is of transplanted seedling that is the same as the eight inch plant. Some have oval leaves and some the narrow leaves. ![]() Second and fourth image of Royal Starr papaya seedlings. These experiments were performed using a 5x4 factorial design (5 substrates x 4 biofertilizer types). First image is of an eight inch papaya plant that still has an oval first leaf. Notice, the seeds are covered in some jelly-like substance. Here’s what you need to do: First, cut a ripe papaya fruit in half and then take out all the seeds. In the second experiment a single inoculation was applied on seedlings, 30 days post emergence. For growing papayas from the seed, the first step is to separate the seeds from the fruit. Two experiments were realized in the first one 2 inoculations were applied, on seeds and afterwards on seedlings, 30 days post emergency. The effect of organic matter and its interaction with the biofertilizers also was evaluated. The effect of time of inoculation (at sowing or after seedling emergence) and the number of applications using 2 biofertilizer ( Azotobacter chroococum and Glomus intraradices) were tested on growth, biomass and nutrition of papaya, at the nursery phase. They are borne in the leaf axils, like the female papaya flowers. Effect of time of inoculation of Azotobacter and mycorrhizal fungi on growth and content nutrient of papaya seedlings in nursery phase. They can pollinate themselves and do not require the presence nearby of another papaya plant. Q: The cheat list is blank! I added USRCHEAT.DAT to the correct folder! Your calendar/time should now be appearing. ![]() Change it all to "show = 1" if you haven't.Then you should find 4 times "show = 0".ini file named "uisettings" into the theme folder, open it. You can try to place these 4 files (clock_colon.bmp, clock_numbers.bmp, day_numbers.bmp, year_numbers.bmp) into a folder named "calendar" within the theme folder. Q: My sav files aren't working! What do I do?Ĭhange the ".sav" or ".SAV" into ".nds.sav". You switch theme by going into Start>Settings>System Settings Tab. On Reset in Game use left or right to enable/disable soft-reset, save settings.On Reset in Game use left or right to enable soft-reset, save settings.Press Start and go to Settings > Patches (R 3x).Turn on your DS and load the Wood R4 firmware: Press (Y) to display the cheat information.Select your cheats (X) and choose your options by selecting the cheats (A).Now select a game and open File Information (Y): On Cheats in Game(AR) use left or right to enable/disable cheats, save settings.Back to file browser, select a game (Y) to open File Information > Settings > Features.Go to Settings > Patches (R 3x), enable Cheats in Game(AR).Copy the usrcheats.dat file and place it in R:\_rpg\cheats\.Confirm to save current settings and restart for the changes to take effect.Press Start to go to Settings and pick a theme from User Interface style.Turn on your DS and load the Wood R4 firmware.Place the custom skins in R:\_rpg\ui\.To use custom skins (you can find them here): The below guide is based on this discussion thread. nds file will act as your boot file instead. If you wish to run another firmware first when booting your ds, don't include _DS_MENU.DAT when installing a Wood firmware. nds file and it'll start the Wood firmware. nds boot file onto the sd card (the location does not matter). ![]() Install the appropriate wood firmware you wish to use.nds launcher that matches the firmware you have downloaded: These are launch files created to boot into the Wood R4 firmware while using another firmware such as YSMenu. Note that the file _DS_MENU.DAT of Wood R4 has the same name as other firmware startup programs, so if you already have another firmware in use, you will have to overwrite it. To install, unzip the archive and copy both the _rpg folder and the _DS_MENU.DAT file to the root of your card. NDS boot files by CoolKill3rX - Wood Firmwares encrypted in.Wood R4 Kernel by Yellow Wood Goblin - FW 1.62 for R4, R4iDSN and Acekard R.P.G.Note: Please note that only Wood R4 for the original R4, R4i Gold (r4ids.cn), R4iDSN () and Acekard R.P.G. There are multiple versions available, for the original R4. It brings exclusive features, ROM compatibility and support along its numerous updates. Wood R4 is an alternative to the original R4 menu. TIP #1: Fish can hide behind aquarium plants. The faster a level is cleared, the more points are awarded. As with all items available for purchase, access to unlocks and purchase things in the store increases as gameplay advances. In the Beach Ball and Plants tab over 100 items are available to decorate the aquarium with statutes or plants. In the Fish tab 8 types of fish are available for purchase. The Store contains three tabs with items available for purchase with gold coins to decorate the aquarium – the Fish, Beach Ball, and Plants icons. The center bar tracks how many fish can be held in the Fish Tank. The Fish Tanks are available to purchase with gold coins. As the fish population grows, Upgrade to larger fish tanks. My Achievements lists all special or bonus plays in the game and assigns extra points when accomplished.Īquariums only hold a certain amount of fish. Every Time a board is cleared using a line bomb and lightning bolt, an Achievement is unlocked. Items in this tab can also be sold to raise gold coins. Items purchased but not used to decorate the aquarium are stored in My Inventory tab. There are a total of eight Themes to buy with gold coins. ![]() The My Backgrounds icon permits the user to change the level Themes. It is organized into four tabs – Fish, Beach Ball, Plants, and Themes.Īs gameplay levels are cleared backgrounds or Themes are unlocked for purchase. The Store contains all of the items available for purchase with gold coins in the game. ![]() They are the Store, My Backgrounds, My Inventory, and My Achievements. The bottom left hand corner of the screen contains four icons. The Move icon permits the aquarium decorations or plants to move.Ĭatch fish with the Net icon.The Sponge icon comes in handy to clean the aquarium.įeed the fish with the Feeder icon. They are Pointer, Move, Net, Sponge, and Feeder. The bottom right hand corner of the screen contains five icons. Gold coins can also be earned by selling items in Inventory or in the Aquarium. ![]() The bar in the center right corner of the screen keeps track of gold available for purchases. Clearing levels, buying fish and decorations, increases gold coin accumulation. Collect all the stars to gain additional bonus points.Įarn gold coins as levels are cleared. TIP: When finished eating the fish generate golden stars. Simply grab the Feeder and feed the fish in the fish tank. Below is a list of instructions and rules that are applicable to all 250 levels.įeed the fish often. Beyond the eleventh level, any of the rules or all of the rules can apply to clear a level. The first eleven levels teach the games rules to players. As fish are added to the aquarium, names are customizable. ![]() Purchase fishes, decorations, fish tanks, background themes, and plants to create an aquarium masterpiece. This enables the players to create a virtual aquarium. Simply select the Settings tab and make appropriate selections.Īs each of the 250 gameplay levels are cleared gold is accumulated. General Gameplay Instructions and RulesĬreate a customizable gameplay experience by entering your gameplay name and selecting video screen size, video screen graphics quality, sound settings, music settings, and volume settings.Only the first eleven that contain the game rules and instructions will be featured. The sections can be accessed in or out of order. This Walkthrough is divided into thirteen sections listed below. While following the general rules of Match 3 games, some twists are present. The Fishdom – Depths of Time is designed to give players a jump start on gameplay action. When finished, your aquarium masterpiece can become a screen saver. At the end of the level, collect silver and gold coins to purchase items to enhance gameplay and build a beautiful aquarium. Collect golden tiles to complete the level. Create matches of 3 or more like tiles by clicking on adjacent tiles to swap positions and clear the board. Fishdom – Depths of Time is a timed electronic Match 3 game. ![]() What I Liked About VeePN? 1.1 Desktop App Jurisdictionġ4 days for a monthly plan, 30 days for all other plans On the good side, VeePN improved a lot in recent years, and with 2,500+ servers in 80+ locations, it can go head-to-head with the big boys on the market. However, beware that its speeds aren’t the fastest and you’ll struggle with unblocking streaming platforms like Netflix, BBC iPlayer, and Hotstar due to its poor streaming capabilities.Īlso, it has occasional connection issues that might stem from its kill switch – a problem known by many in this VPN. With no IP leaks and excellent 24/7 support, VeePN is very well worth your money. As mentioned, it’s pretty cheap and its 5-year plan is one of the best VPN deals on the market. In addition, features like Double VPN, ad-blocker, and WireGuard support are more than welcome given its affordable price.īased in Panama, VeePN is a great no-logging VPN that backs everything up with RAM-based servers that surely have a lot to offer in terms of privacy. ![]() It offers awesome mobile and desktop apps that are as feature-rich as some more expensive providers. VeePN is a provider that does a lot of things right. To get answers to these questions, you’ll have to read my full, in-depth VeePN review for 2023. Is it any good, though? Is it better than its more popular competitors in the price range? However, it stood the test of time and spent more than a few years on the market, being one of the cheapest premium providers you can get. Yes, it isn’t the most popular option and that’s evident. VeePN is especially interesting, as it made quite a few improvements in the past few years. ![]() We have plenty of cheap providers on the market, such as Surfshark, CyberGhost, and of course – VeePN. Well, in the VPN world, a better VPN isn’t necessarily a more expensive one. They include a privacy-friendly jurisdiction, lots of security features, a no-logs policy, and for some people, even a slightly higher price that would indicate a high level of quality. When talking about safe, secure, and trustworthy VPNs, there are a lot of factors that contribute to that status. For alternatives, Express VPN or Astrill are great paid tools, and Cocoon or OpenVPN are excellent free options.We earn commissions using affiliate links. There are also versions for Mac, Android and iOS devices. In each plan, you can connect up to ten devices at once, and for an extra fee, until 100, Where can you run this program? There are three coverage plans, including a month-, year-, or 5-year subscription. VeepN is not a free service however, you can take advantage of its week-long free trial before you pay. The No Log policy is another excellent feature, ensuring that the software doesn't collect any of your sensitive information. It may downgrade the already-average server speed, though. With regards to the extras, you can double down your security with the Double VPN feature, allowing you to connect to two servers and mix two protocols. The software lets you manually enable ad-blocks, prevent malicious websites from opening, and stop online tracking. There's also an automatic system for public WiFi security, as well as a Kill Switch for shutting down unstable connections. VeepN uses military-grade 256-bit encryption to guarantee that your true location remains hidden. All servers come with unrestricted switching and unlimited bandwidth. Connecting you to them ensures online anonymity. It boasts over 2,500 servers across the world in 50 different locations. With all essential functions and several extras, VeepN is a VPN program that offers privacy and security for those browsing the Internet. The mounting bracket features a large opening for easy access to wiring, and a side load battery drawer provides quick battery replacement without the need to remove the alarm from the ceiling or wall. The alarm is also designed for easy maintenance. This alarm is designed for easy installation with its Perfect Mount System, which includes a gasketless base and a mounting bracket that keeps the alarm secure over a wide rotation range to allow for perfect alignment. However, with the hardwired bridge unit (model SA520B), hardwired and wireless models can be interconnected together on the same mesh network. Ordinarily, wireless and hardwired alarms cannot work together on the same interconnected network. Up to 18 total units can be interconnected, wireless or hardwired: with a maximum of 12 smoke alarms and 6 carbon monoxide alarms. The mesh network of alarms re-routes and resends the signal via other First Alert alarms, providing a greater chance all alarms will receive the signal. First Alert Interconnect Alarms operate on a mesh network that integrates multiple wireless or wired alarms for better safety and response in an emergency. This First Alert Alarm can be integrated into a mesh network with other First Alert Alarms using “Interconnect Technology”. After the alarm condition subsides, the initiating unit will store in memory or "latch" the information and begin to flash the green LED indicator two seconds on, two seconds off, signaling the source of smoke. When interconnected in a series of detectors, the unit that triggered the alarm rapidly flashes its red LED indicator. Additionally, the Latching Alarm Indicator easily identifies the initiating alarm even after the alarm condition has subsided.Īs part of the Smart Technology system, the Latching Alarm feature remembers which detector in your home initiated an alarm. Alarms that do not have the "Smart Interconnect" feature remain silent during a CO alarm. When CO is detected, all alarms sound the CO horn pattern. When smoke is detected, all alarms sound the distinctive smoke horn pattern. The alarm includes "Smart Interconnect" technology, enabling it to interconnect with other BRK Smoke, Heat, and "Smart Interconnect" CO Alarms. Can be interconnected with other BRK Alarms.Dust cover included to keep the alarm clean during construction.Improved UV resistance prevents discoloration over time.Intelligent Sensing Technology that reduces unwanted or nuisance alarms.It connects directly to your home electrical system and comes with a 10 year lithium battery backup. ![]() This detector features ionization technology and an electromechanical sensor with Intelligent Sensing Technology that reduces unwanted or nuisance alarms.
![]() Representative scatter plots show similar analysis performed on cells elicited from wild-type mice after 6 hours of stimulation with SES in combination with sgp130 (150 ng per mouse) or IFN-γ –/– mice after stimulation with SES in combination with HYPER-IL-6 (40 ng per mouse). ( a) Annexin V/PI staining of leukocytes. Modulation of IL-6 signaling in vivo affects apoptotic clearance of PMN in SES-induced peritoneal inflammation. After 1 hour, mice were sacrificed and IL-6 was quantified (* P < 0.05 versus PBS alone ** P < 0.05, a significant increase versus the additive value of IL-1β plus IFN-γ alone). ( e) Wild-type mice were intraperitoneally administered with PBS, IL-1β (100 ng per mouse), IFN-γ (0.5 U per mouse), or a combination of IL-1β and IFN-γ at these doses. Results are representative of three separate experiments performed with HPMC from different donors. ( d) Composition of the NF-κB complex was determined by supershift using antibodies against p50 (lane 2) and p65 (lane 3). At the indicated intervals, nuclear extracts were prepared and NF-κB activation was monitored by EMSA. ( c) HPMC were stimulated with medium alone (lane 1), HYPER-IL-6 (500 pg/ml, lane 2), IFN-γ (100 U/ml, lane 3), IL-1β (100 pg/ml, lane 4), or a combination of IL-1β and IFN-γ (lane 5). Representative results for three separate experiments are shown. ( b) Northern blot analysis of total RNA isolated from HPMC incubated for 3 hours with medium and IL-1β (100 pg/ml) in the presence or absence of IFN-γ (100 U/ml). At specific time points, IL-6 levels were quantified using ELISA (* P < 0.05, a significant increase versus the additive value of IL-1β plus IFN-γ alone). Growth-arrested HPMC were ( a) incubated with medium alone or IL-1β (100 pg/ml) in the presence or absence of IFN-γ (100 U/ml). Regulation of IL-6 production by IL-1β and IFN-γ in vitro and in vivo. These data emphasize a pivotal role for IFN-gamma in regulating innate immunity through control of both the recruitment and clearance phases of PMN trafficking. Examination of the leukocyte infiltrate from IFN-gamma-/-, IL-6-/-, and wild-type mice showed that apoptosis was aberrant in the absence of IFN-gamma and IL-6 as a result of impaired sIL-6R signaling. ![]() Although HYPER-IL-6 attenuated PMN influx in IFN-gamma-/- mice, IFN-gamma had no effect on PMN infiltration in IL-6-/- mice. To test whether local IL-6 signaling modulated PMN recruitment, inflammation was induced in IFN-gamma-/- and IL-6-/- mice and cytokine signaling adapted by intraperitoneal sIL-6R-IL-6 fusion protein (HYPER-IL-6) or IFN-gamma. Reconstitution of IFN-gamma signaling restored the rate of PMN infiltration and IL-6 levels and was accompanied by normalization of PMN-activating CXC chemokine expression. This defect in PMN recruitment was also associated with the suppressed intraperitoneal expression of IL-1beta and IL-6. Induction of peritoneal inflammation in IFN-gamma-deficient (IFN-gamma-/-) mice emphasized that the initial rate of PMN recruitment was impaired. We now report that IFN-gamma controls PMN infiltration and modulates IL-6 signaling through its soluble receptor (sIL-6R) to promote their apoptosis and clearance. Regulated recruitment and clearance of neutrophils (PMN) is the hallmark of competent host defense and resolution of inflammation. |
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